Table 1 Radiologic characteristics of study population in TRAIAC groups.

From: Analysis of CT morphologic features and attenuation for differentiating among transient lesions, atypical adenomatous hyperplasia, adenocarcinoma in situ, minimally invasive and invasive adenocarcinoma presenting as pure ground-glass nodules

 

Total

TRAs

AAHs

AISs

MIAs

IACs

H

p

pGGNs n [%]

255

64 [25.1]

22 [8.6]

37 [14.5]

108 [42.4]

24 [9.4]

\

\

Age (years)

55 (43–62)

51 ± 13

57 ± 9

52 ± 13

55 (41–63)

61 ± 10

13.47

0.009**

Gender male [%]

80 [31.4]

27 [42.2]

3 [13.6]

10 [27]

27 [25]

13 [54.2]

14.84

0.005**

Lobe location

      

14.12

0.590

RUL

92

17

5

16

43

11

  

RML

28

8

3

3

12

2

  

RLL

44

12

4

8

18

2

  

LUL

60

15

9

6

24

6

  

LLL

31

12

1

4

11

3

  

Location

      

18.4

0.018*

Inner

34 [13.3]

10

3

4

13

4

  

Middle

108 [42.4]

38

5

13

40

12

  

Peripheral

113 [44.3]

16

14

20

55

8

  

Nodule size (mm)

7 (5–9)

5 (4–6)

5 (4–6.5)

7 (5.5–8)

13 (11.3–17)

14 ± 5.7

90.77

0.000****

Shape

      

28.54

0.000****

Round or oval

88

9

4

13

46

18

  

Irregular

167

55

18

24

62

8

  

Margin

      

37.23

0.000****

Clear

161

22

17

24

83

15

  

Unclear

66

29

5

11

16

5

  

Fuzzy

28

0

0

2

9

4

  

Air bronchogram

31

2

1

2

13

13

47.33

0.000****

Vessel change

      

80.43

0.000****

Normal

149

59

18

29

39

4

  

Gather/Dilated

106

5

4

8

69

20

  

Pleural change

27

2

0

2

15

8

21.78

0.000****

Creep growing sign

63

2

1

8

43

9

36.38

0.000****

Bubble-like lucency

21

0

1

0

12

8

30.65

0.001***

Maximum CT value

−585 (−668–475)

−655 (−736–588)

−656 (−710–572)

−587 ± 103

−519 (−639–439)

−457 ± 105

64.77

0.000****

Lung parenchyma CT value

−881 (−899–857)

−874 ± 35

−881 (−899–856)

−877 ± 28

−883 (−901–860)

−877 ± 30

1.036

0.904

Difference CT value

290 (201–404)

209 (144–295)

218 (173–283)

263 (230–332)

359 (245–441)

402 (331–543)

66.7

0.000****

Relative CT value

1.49 (1.30–1.83)

1.32 (1.20–1.48)

1.33 (1.25–1.50)

1.42 (1.33–1.62)

1.69 (1.40–2.00)

1.85 (1.69–2.95)

67.55

0.000****

  1. RUL, right upper lobe; RML, right middle lobe; RLL, right lower lobe; LUL, left upper lobe; LLL, left lower lobe. Significant level marks: p < 0.05 *p < 0.01 **p < 0.001 ***p < 0.0001 ****.