Figure 3 | Scientific Reports

Figure 3

From: Low-grade glioma harbors few CD8 T cells, which is accompanied by decreased expression of chemo-attractants, not immunogenic antigens

Figure 3

Neo-antigens nor CGAs are differentially expressed in LGG versus HGG. (a) The total number of mutations in coding regions in HGG (n = 5) and LGG (n = 5) shows a higher mutational load in HGG (top). This difference is also observed when selecting for nonsynonymous mutations that are expressed (middle). The number of predicted neo-antigens were however very low and did not differ between LGG and HGG (bottom). See materials and methods for details. (b) Number of expressed CGAs was similar in LGG and HGG samples. Mann-Whitney U test. *P < 0.05.

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