Figure 5 | Scientific Reports

Figure 5

From: Low-grade glioma harbors few CD8 T cells, which is accompanied by decreased expression of chemo-attractants, not immunogenic antigens

Figure 5

Decreased gene-expression of T cell trafficking molecules in LGG versus HGG. RT-qPCR was performed for HGG (n = 20) and LGG (n = 20) to determine gene expression levels of (a) the chemo-attractants CXCL9 and CXCL10, adhesion molecule ICAM1 and (b) the T cell effector molecule GZMK. Each dot represents an individual sample. Relative expression levels (2−ΔCt) are shown according to log scale. Black bars show the median value. Expression levels of HGG and LGG are compared using the Mann-Whitney U test and p-values are FDR-corrected for multiple testing. ***P < 0.001, **P < 0.01, *P < 0.05, NS = not significant.

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