Figure 1 | Scientific Reports

Figure 1

From: Identification of a novel synthetic lethal vulnerability in non-small cell lung cancer by co-targeting TMPRSS4 and DDR1

Figure 1

(A) Schematic representation of the strategy used to identify genes coexpressed with TMPRSS4 in public databases. (B) Protein-protein network interactions analysis using STRING. Nine of the genes were significantly interconnected (FDR < 0.05). (C) Significant positive correlation between TMPRSS4 and DDR1 expression in LUAD and LUSC patient samples from Bild, Lee and TCGA databases, and in Cancer Cell Line Encyclopedia (CCLE) and CIMA cell lines.

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