Figure 2 | Scientific Reports

Figure 2

From: Plasmodium Infection Induces Dyslipidemia and a Hepatic Lipogenic State in the Host through the Inhibition of the AMPK-ACC Pathway

Figure 2

Lipid profile analysis in the liver (A,B) and white adipose tissue (WAT; C,D) of mice infected with P. chabaudi. The graphs show lipid classes obtained through thin-layer chromatography and percentages determined by densitometric analysis. Hepatic (A) and WAT (C) analyses of neutral lipids showing the percentage of triacylglycerol (TAG), cholesterol ester (CHOE), free fatty acid (FFA), cholesterol (CHO), monoacylglycerol (MAG), and phospholipid (PHO) in respective tissues of control (CTR, n = 14) versus infected (INF, n = 14) mice. Insets in (A,C) upper right represent TAG concentration obtained using enzymatic colorimetric assays. Hepatic (B) and WAT (D) analyses of phospholipids showing the percentage of phosphatidic acid (PA), phosphatidylethanolamine (PE), phosphatidylcholine (PC), phosphatidylinositol (PI), sphingomyelin (SM), and lysophosphatidylcholine (LPC) in respective tissues of CTR versus INF animals. Statistical analyses: multiple t-test. Values are presented as mean ± standard error. *p < 0.05 and **p < 0.01.

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