Figure 4

(a) Unadjusted and (b) adjusted associations of EPO levels with annualized eGFR slope. In the multivariable analysis, we adjusted for age, sex, eGFR, urine albumin-to-creatinine ratio, hemoglobin, diabetic retinopathy, systolic blood pressure, hemoglobin A1c, use of angiotensin-converting enzyme inhibitors or angiotensin receptors, statin use, fibroblast growth factor 23, 25-hydroxyvitamin D, and urinary liver-type fatty acid-binding protein. The solid line represents the point of estimate and the dashed line represents the 95% CI. Abbreviations: EPO, erythropoietin; eGFR, estimated glomerular filtration rate.