Table 1 Clinicopathologic characteristics of patients and univariate logistic analysis in patients.

From: Development and validation of a prognostic nomogram for predicting post-operative pulmonary infection in gastric cancer patients following radical gastrectomy

Clinicopathological parameters

Development set (n = 1728)

Validation set (n = 741)

N

Pulmonary infection

OR (95% CI)d

P

N

Pulmonary infection

OR (95% CI)d

P

Negative

Positive

Negative

Positive

ALL

 

1728

1688

40

  

741

716

25

  

Gender

Male

1154

1124

30

1.51 (0.78–2.23)

0.267

470

455

15

0.86 (0.05–1.68)

0.718

Female

574

564

10

Ref

 

271

261

10

Ref

 

Age (\(\bar{{\rm{\chi }}}\) ± S)

  

55.18 ± 10.62

57.45 ± 11.26

1.02 (0.99–1.05)

0.183

—

55.90 ± 10.56

56.72 ± 7.19

1.01 (0.97–1.05)

0.701

Body mass index (kg/m2)e

<18.5

205

197

8

0.80 (0.25–1.35)

0.435

93

92

1

2.28 (1.57–2.98)

0.022

18.5–25.0

1281

1255

26

  

539

523

16

  

>25.0

242

236

6

  

109

101

8

  

Smoking (pack-y)

 

13.99 ± 20.81

22.25 ± 24.04

1.01 (1.00–1.03)

0.015

—

14.23 ± 20.53

13.64 ± 25.80

1.00 (0.98–1.02)

0.889

ASA score

1 + 2

1539

1508

31

Ref

0.022

664

643

21

Ref

0.355

3 + 4

189

180

9

2.43 (1.67–3.19)

 

77

73

4

1.68 (0.58–2.77)

 

COPD

Yes

61

56

5

4.16 (3.19–5.14)

0.004

20

16

4

8.33 (7.16–9.51)

0.000

No

1667

1632

35

Ref

 

721

700

21

Ref

 

Comorbidities excepting COPD

Yes

480

467

13

1.26 (0.59–1.93)

0.501

203

192

11

2.14 (1.34–2.95)

0.064

No

1248

1221

27

Ref

 

538

524

14

Ref

 

Anemiaa

No

1086

1065

21

Ref

0.174

473

461

12

Ref

0.134

Yes

642

623

19

1.55 (0.92–2.18)

 

278

265

13

1.84 (1.04–2.64)

 

Albumin (g/L)

≥35

1361

1336

25

Ref

0.013

573

554

19

Ref

0.872

<35

367

352

15

2.28 (1.63–2.93)

 

168

162

6

1.08 (0.15–2.01)

 

Pre-operative blood transfusion

Yes

161

151

10

3.39 (2.66–4.13)

0.001

62

60

2

0.95 (−0.52–2.42)

0.946

No

1567

1537

30

Ref

 

679

656

23

Ref

 

Operation procedure

Open

1339

1301

38

5.65 (4.23–7.08)

0.017

565

544

21

1.66 (0.58–2.74)

0.359

Laparoscopy

389

387

2

Ref

 

176

172

4

Ref

 

Extent of gastrectomy

Total

415

400

15

1.93 (1.28–2.58)

0.047

166

158

8

1.66 (0.80–2.52)

1.359

Subtotalb

1313

1288

25

Ref

 

575

558

17

Ref

 

Combined multi-organ resection

Yes

162

151

11

3.86 (3.15–4.57)

0.000

58

54

4

2.34 (1.23–3.44)

0.132

No

1566

1537

29

Ref

 

683

662

21

Ref

 

Operation time (hour)

>4

369

352

17

2.81 (2.17–3.44)

0.002

165

153

12

3.40 (2.59–4.20)

0.003

≤4

1359

1336

23

Ref

 

576

563

13

Ref

 

Amount of bleeding (ml)

>300

341

328

13

2.00 (1.32–2.67)

0.044

153

146

7

1.52 (0.63–2.41)

0.359

≤300

1387

1360

27

Ref

 

588

570

18

Ref

 

Intra-operative blood transfusion

Yes

141

130

11

4.55 (3.83–5.26)

0.000

56

54

2

1.07 (−0.41–2.54)

0.932

No

1587

1558

29

Ref

 

685

662

23

Ref

 

Tumor location

Upper third

145

137

8

3.90 (3.04–4.76)

0.002

71

67

4

1.83 (0.70–2.95)

0.293

Middle third

431

416

15

2.41 (1.70–3.11)

0.014

164

159

5

0.96 (−0.06–1.98)

0.942

Lower third

1152

1135

17

Ref

 

506

490

16

Ref

 

Tumor size (cm)e

<2.5

373

370

3

2.06 (1.56–2.55)

0.004

144

139

5

1.13 (0.51–1.75)

0.692

2.5–5.0

949

928

21

  

431

418

13

  

>5.0

406

390

16

  

166

159

7

  

TNM stagec,e

I

449

444

5

1.38 (0.97–1.79)

0.124

200

195

5

1.41 (0.89–1.92)

0.194

II

365

354

11

  

149

146

3

  

III

914

890

24

  

392

375

17

  
  1. ASA: American Society of Anesthesiologist; COPD: chronic obstructive pulmonary disease. Ref: reference.
  2. aDefines as hemoglobin level <120 g/L in male and <110 g/L in female.
  3. bSubtotal contains two kinds of extent of gastrectomy: distal and proximal subtotal.
  4. cTumor stages are based on 7th edition of the Union for International Cancer Control TNM classification.
  5. dOR: Odds Ratio, it was derived from univariate logistic analysis. CI: confidence interval
  6. eThese factors are continuous variables, and in univariate logistic analysis there are no reference category groups.
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