Figure 3
From: A large intragenic deletion in the CLCN1 gene causes Hereditary Myotonia in pigs
Nucleotide sequence analysis at the deletion junction of the CLCN1 gene in myotonic pigs. Upper panel: Alignment of the genomic relevant consensus sequence of myotonic pigs against the pig genome. Note abundant short interspersed nuclear elements (SINE) within the CLCN1 gene in pigs. Middle panels: Higher sequence resolution at both breakpoints indicates that the 5′-breakpoint is located 102 nucleotides downstream of a MIR3 repeat and the 3′-breakpoint lies within a Pre0_SS repetitive element. Lower panel: Analysis of the regions flanking both breakpoints reveal an identical TGGGTTTAA motif close to both breakpoints.
