Figure 3
L. reuteri effects on gut microbiota. Twelve week old C57BL/6 and Rag KO male mice were supplemented with water or L. reuteri for 4 weeks as indicated in Fig. 2. Fecal samples were collected at the day of harvest and analyzed by 16S rRNA sequencing as described in the methods. (A) Plots of alpha-diversity metrics of observed operational taxonomic units (OTUs) (richness) and Shannon diversity (richness and evenness) of the different treatment groups. (B) Principle coordinate analysis of beta-diversity based on Bray-Curtis (richness and evenness) of the different treatment groups. WT/C = wild-type control, WT/LR = wild-type L. reuteri treated, KO/C = Rag1 KO control, KO/LR = Rag1 KO L. reuteri treated. N = 9–10/group.
