Table 5 The results of the joint pathway analysis from discriminating metabolites between EG and RG groups.
From: NMR-based metabolomics in pediatric drug resistant epilepsy – preliminary results
No. | Pathway name | Total | Hits | p-value | −log(p) | Holm p | Impact |
|---|---|---|---|---|---|---|---|
1 | Glycine serine and threonine metabolism | 68 | 2 | 0.013 | 4.317 | 1 | 0.708 |
2 | Citrate cycle (TCA cycle) | 50 | 1 | 0.136 | 1.989 | 1 | 0.576 |
3 | Glutathione metabolism | 75 | 1 | 0.199 | 1.611 | 1 | 0.133 |
4 | Glyoxylate and dicarboxylate metabolism | 53 | 2 | 0.008 | 4.805 | 0.654 | 0.057 |
5 | Cyanoamino acid metabolism | 12 | 1 | 0.034 | 3.375 | 1 | 0 |
6 | Arginine and proline metabolism | 102 | 1 | 0.263 | 1.333 | 1 | 0.016 |
7 | Primary bile acid biosynthesis | 63 | 1 | 0.169 | 1.772 | 1 | 0 |
8 | Pyruvate metabolism | 64 | 1 | 0.172 | 1.758 | 1 | 0 |
9 | Porphyrin and chlorophyll metabolism | 70 | 1 | 0.187 | 1.675 | 1 | 0 |
10 | Aminoacyl-tRNA biosynthesis | 87 | 1 | 0.228 | 1.476 | 1 | 0 |
11 | Glycolysis/Gluconeogenesis | 91 | 1 | 0.237 | 1.435 | 1 | 0 |
