Figure 5
Rectal and iBAT temperature time curves following the first norepinephrine injection for two KO mice (a,b) and two WT mice (c,d). Rectal temperature (blue triangles) as well as iBAT temperature, as measured by XeMRT using a non-localized (red circles) 129Xe spectroscopy sequence (i.e. excitation followed by acquisition), as a function of time following the first norepinephrine injection. A second norepinephrine injection (red dashed line labelled “2nd NE”) in both WT and KO was able to elicit a second thermogenic response in iBAT. Rectal temperature errors (±0.1 °C) are within the size of the data points.
