Figure 8
Comparison between non-localized and localized 129Xe spectra used to determine iBAT temperature in a KO mouse. (a) Non-localized 129Xe spectrum (blue) overlaid onto a localized 129Xe spectrum (red). A more than 500-fold reduction in SNR is seen in the localized spectra compared to the non-localized spectra. (b) Non-localized spectrum (green) distorted by lipid-dissolved xenon spin components located outside the shimmed volume. (blue) Same non-localized spectrum obtained after filtering out the fast-relaxing spin components. (red) Localized spectrum acquired on the same mouse. (c) Corresponding FID signal obtained with the non-localized spectroscopy sequence. Fast-relaxing spin components are observed only during the first few milliseconds of the FID’s evolution (yellow dotted box). (d) First 10 ms of the FID showing the contribution of fast relaxing spin components mainly in the first 4 ms (yellow dotted box).
