Figure 6
From: Modeling Living Cells Within Microfluidic Systems Using Cellular Automata Models
Summary of the development of a simulation process for a multi-chamber and multi-channel organ-on-a-chip device for modelling metastases: (a) Computer-aided design (NX-8.5). (b) CAD incorporated to Matlab. (c) Lattice with the allowed and forbidden zones. (d) Results from a dynamic proliferation and interaction process, which starts by seeding different cell types in the inlets (green and blue) and shows the effect of adding a drug (pink), whose diffusion and impact on cells is also modelled. Selected representative iterations are shown, including the initial state, the addition of drug and the final state after complete colonization. Scale bar: 4 mm.
