Figure 6 | Scientific Reports

Figure 6

From: Simultaneous electrophysiological and morphological assessment of functional damage to neural networks in vitro after 30–300 g impacts

Figure 6

Nuclear movement in different neurons from three networks subjected to tangential acceleration. Three panels show neurons t-minutes before and after impact (t = 0) with quantitative graphs of nucleolar movements in the right column. Movement is quantified in terms of degrees of rotation in a horizontal plane (left ordinate, closed symbols) and centrifugal and centripetal drift expressed as percent of the nuclear radius (right ordinate, open symbols). Positive and increasing degree values indicate a counter clockwise displacement from origin, while negative and decreasing values represent a clockwise motion. In all cases movement starts within 30 min of impact. Transitions between fast, slow, and no rotation are occasionally accompanied by sudden jumps (arrows). Nucleolar drift is irregular whereas rotation is more consistent. Direction of impacts: right to left. Five multiple impacts were administered in 5 to 8 second intervals at 250 g each. Bar size: 20 um.

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