Figure 4 | Scientific Reports

Figure 4

From: Elevated FGF23 and disordered renal mineral handling with reduced bone mineralization in chronically erythropoietin over-expressing transgenic mice

Figure 4

Chronic EPO over-expression induced FGF23 expression in spleen and liver of Tg6 mice. FGF23 mRNA levels were examined in (A) femur, (B) liver, and (C) spleen of 6–8 weeks old female Tg6 mice versus control. Expression levels of FGF23 were normalized to ribosomal 18 s. Data are means ± s.e.m.; n = 5–7 for each group of mice. Significance was determined by unpaired t test and indicated ***p < 0.001.

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