Figure 5 | Scientific Reports

Figure 5

From: Elevated FGF23 and disordered renal mineral handling with reduced bone mineralization in chronically erythropoietin over-expressing transgenic mice

Figure 5

Normal 1,25 (OH)2 vitamin D3 metabolism in Tg6 mice. Expression of the enzymes metabolizing 1,25 (OH)2 vitamin D3 and the vitamin D receptor (VDR) was examined by immunoblotting in kidney and ileum of 6–8 weeks old female Tg6 mice and their controls. (A) Renal expression of Cyp24a1 and the vitamin D receptor (VDR) and (B) ileal expression of Cyp24a1 and the VDR. For immunoblots, all membranes were stripped and re-probed for β-actin. Graphs show the ratio of the protein of interest over β-actin. Data are means ± s.e.m.; n = 5 for each group of mice.

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