Table 2 MicroCT bone measurements.

From: Elevated FGF23 and disordered renal mineral handling with reduced bone mineralization in chronically erythropoietin over-expressing transgenic mice

 

WT

Tg6

Total volume (TV) (mm3)

2.97 ± 0.03

3.12 ± 0.04*

Bone volume (BV) (mm3)

1.15 ± 0.05

1.28 ± 0.04

BV/TV (%)

38.9 ± 1.5

41.2 ± 1.0

Trabecular number Tb.N (1/mm)

2.09 ± 0.21

2.83 ± 0.22*

Trabecular thickness Tb.Th (mm)

0.07 ± 0.01

0.07 ± 0.01

Trabecular separation Tb.Sp (mm)

0.20 ± 0.01

0.17 ± 0.01*

Connectivity density Conn.D (1/mm3)

51.5 ± 8.9

111.0 ± 13.4**

  1. Parameters from microCT analysis of femora of 6–8 weeks old female Tg6 mice and littermates. Total bone volume (TV), bone volume (BV), trabecular bone fraction (BV/TV), thickness of the trabeculae (Tb.Th), trabeculae number (Tb.N), connectivity density (Conn.D), and trabecular separation (Tb.Sp) values are given for Tg6 and control groups. Data is presented as mean ± s.e.m.; n = 9 for each group of mice, data were analysed by unpaired Student’s t-test with *p < 0.05 and **p < 0.01.
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