Table 3 Performance of the top diagnostic miRNA biomarkers.

From: EV-associated miRNAs from pleural lavage as potential diagnostic biomarkers in lung cancer

miRNA

AUC

Accuracy

95% CI

Sensitivity

Specificity

Logistic model on the 2:1 cohort

hsa-miR-1-3p_477820_mir

0,923

0,941

[0.936; 0.946]

0,938

0,943

hsa-miR-144-5p_477914_mir

0,925

0,878

[0.872; 0.883]

0,776

0,941

hsa-miR-150-5p_477918_mir

0,937

0,825

[0.818; 0.831]

0,666

0,925

Logistic model on the whole cohort

hsa-miR-1-3p_477820_mir

0,914

0,941

[0.803; 0.993]

0,929

0,95

hsa-miR-150-5p_477918_mir

0,939

0,912

[0.763; 0.981]

0,857

0,95

hsa-miR-144-5p_477914_mir

0,925

0,882

[0.725; 0.967]

0,786

0,95

  1. AUC values, accuracy, sensitivity, specificity and 95% of confidence intervals are summarized for those miRNAs which were selected for the highest diagnostic performance on the 2:1 cohort (on top) and the whole cohort (below).
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