Figure 4 | Scientific Reports

Figure 4

From: Resistin expression in human monocytes is controlled by two linked promoter SNPs mediating NFKB p50/p50 binding and C-methylation

Figure 4

Haplotype dependent acetylation of the RETN gene locus. (a) Genome browser view of the RETN gene locus. The figure depicts the RETN region analyzed for H3K27 acetylation, in reference to the location of rs3219175. Representative H3K27me3 ChIP-seq tracks for monocytes from individuals of the three rs3219175 genotypes (AA, AG and GG) are shown. All acetylation tracks are plotted on the same fold-enrichment scale. (b) Read depth analysis. The bar chart displays the number of sequencing reads covering the A allele (pink) and the G allele (green) of rs3219175 within 32 individuals. The blue line represent peak heights of the peaks for each genotype (c) Peak height association. The boxplots indicate the height of the H3K27ac peak in reference to the rs3219175 genotype.

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