Table 2 The associations of RETN SNP rs3219175 with plasma biomarkers.

From: Resistin expression in human monocytes is controlled by two linked promoter SNPs mediating NFKB p50/p50 binding and C-methylation

Analytes

Position

Allele 1

n

Regression coefficient

Standard error

t statistic

p

AA genotype

GG genotype

Resistin

7733855

A

197

2.76E-01

0.01641

16.79

1.154E-39

4.476 (±0.058)

3.984 (±0.024)

TGFB2

7733855

A

197

−0.04273

0.01475

−2.896

0.004207

2.486 (±0.049)

2.569 (±0.019)

TGFB1

7733855

A

187

−0.04649

0.01843

−2.522

0.01252

2.918 (±0.056)

2.963 (±0.027)

S100-B

7733855

A

92

−0.1348

0.0553

−2.437

0.01681

0.883 (±0.547)

1.198 (±0.065)

MCP-2

7733855

A

187

−0.03991

0.01673

−2.385

0.01809

1.270 (±0.0.052)

1.309 (±0.024)

IL-8

7733855

A

179

−0.1777

0.07641

−2.326

0.02118

2.858 (±0.048)

2.881 (±0.017)

sTNFRI

7733855

A

197

−0.03211

0.01412

−2.274

0.02405

0.311 (±0.397)

0.526 (±0.089)

sRAGE

7733855

A

198

0.07566

0.0346

2.187

0.02996

2.087 (±0.055)

1.991 (±0.053)

sTNFRII

7733855

A

197

−0.02976

0.01448

−2.055

0.04119

3.554 (±0.072)

3.571 (±0.020)

sVEGFR2

7733855

A

197

−0.02469

0.01205

−2.049

0.04181

4.015 (±0.061)

4.071 (±0.016)

MIG

7733855

A

198

−0.06777

0.03331

−2.035

0.04325

2.553 (±0.147)

2.601 (±0.050)

  1. The table summarizes the association data of plasma proteins correlating with rs3219175 (genomic position within chr19: 7733855) with nominal p values < 0.05. For each analyte the allele 1 (minor allele), the number of samples (n), regression coefficient, standard error, t statistic and the nominal p value as well as the average plasma concentration in individuals of the AA and GG genotype are listed.
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