Figure 1
From: Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment
Manhattan plots for high and low/mid frequency hearing loss. The significant (P < 5*10−8; red horizontal line) and suggestive (P < 1*10−6; blue horizontal line) associations are coloured green for HIGH (high frequency hearing loss) and yellow for LOW/MID (low and mid frequency hearing loss). This colour scheme illustrates that high and low/mid frequency hearing loss have different genetic backgrounds. We found three genome-wide significant SNPs: one at chromosome 2 (rs6740893; LOW/MID phenotype), one at chromosome 3 (rs2332035; HIGH phenotype), and one at chromosomes 8 (rs9298078; LOW/MID phenotype).
