Table 3 The odds [95%CI] of the grandchild having myopia at age 7 if the maternal grandmother smoked.

From: Grandmothers’ smoking in pregnancy is associated with a reduced prevalence of early-onset myopia

Population

Unadjusted OR [95%CI]

Adjusted (A) OR [95%CI]

Adjusted (B) OR [95%CI]

All children

N = 6995

N = 6565

N = 6995

Boys + Girls

0.62 [0.41, 0.91]*

0.63 [0.41, 0.95]*

0.60 [0.40, 0.91]*

Boys only

N = 3557

  

0.61 [0.35, 1.08](*)

DNE

DNE

Girls only

N = 3438

 

N = 3261

0.62 [0.36, 1.07](*)

 

0.60 [0.33, 1.07](*)

Mother non-smoker

N = 5953

N = 5609

N = 5953

Boys + Girls

0.57 [0.37, 0.89]*

0.59 [0.37, 0.94]*

0.57 [0.36, 0.90]*

Boys only

N = 3017

  

0.52 [0.27, 0.99]*

DNE

DNE

Girls only

N = 2936

  

0.62 [0.34, 1.14]

DNE

DNE

Mother smoked

   

Boys + Girls

N = 1020

  

0.95 [0.36, 2.47]

DNE

DNE

Boys only

N = 531

  

1.29 [0.34, 4.85]

DNE

DNE

Girls only

N = 489

  

0.66 [0.16, 2.79]

DNE

DNE

  1. The table shows the unadjusted and adjusted odds, for (a) all children; (b) for children whose mothers had not smoked in pregnancy, and (c) for children whose mothers had also smoked in pregnancy. Adjustments are: (A) for features of the grandparents’ background; (B) also including maternal vision impairments. (In bold are the adjusted results significant at P < 0.01).
  2. DNE = did not enter; OR = odds ratio; AOR = adjusted odds ratio;
  3. NS = P > 0.10; (*)P < 0.10; *P < 0.05; **P < 0.01; ***P < 0.001.
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