Table 2 Site of TB disease and diagnosis basis of 28 TB patients during pregnancy.

From: Retrospective Analysis of 28 Cases of Tuberculosis in Pregnant Women in China

Case

Site of TB disease

Diagnosis basis

1

Miliary, pleural and cerebral

Miliary shadowing on chest CT. Intracerebral tuberculomas on head MRI. Pleural exudatum, monocyte(MONO)% 82% and adenosine deaminase(ADA) 56.3 U/L. Positive blood T-SPOT.TB. Smear, culture and Xpert MTB/RIF were not done in sputum or pleural effusion.

2

Miliary, cerebral and meninges

Miliary shadowing on chest CT. Intracerebral tuberculomas on head MRI. Abnormal CSF. Positive blood T-SPOT.TB. Sputum smear and culture were negative, CSF smear and culture were not done, and Xpert MTB/RIF was not done in sputum or CSF.

3

Pleural

Pleural exudatum, MONO% 91% and ADA 62.2 U/L. Positive blood and pleural T-SPOT.TB. Smear, culture and Xpert MTB/RIF were not done in sputum or pleural effusion.

4

Pleural

Complained of fever and chest pains for 3 weeks. Less pleural effusion and no extraction. Positive blood T-SPOT.TB. Response to treatment. Smear, culture and Xpert MTB/RIF were not done in sputum or pleural effusion.

5

Pleural

Pleural exudatum, MONO% 66.3% and ADA 57.4 U/L. Positive blood T-SPOT.TB. Pleural effusion culture positive. Strain identification is M. Tuberculosis complex. Sputum smear and culture were negative.

6

Pulmonary and pleural

Lung infiltrate on chest CT. Pleural exudatum, MONO% 93.6% and ADA 41.9 U/L. Positive blood T-SPOT.TB. Smear, culture and Xpert MTB/RIF were negative in sputum and pleural effusion.

7

Pulmonary and pleural

Lung infiltrate on chest CT. Pleural exudatum, MONO% 98% and ADA 34 U/L. Positive blood T-SPOT.TB. Sputum culture positive. Strain identification is M. Tuberculosis complex. Sputum Xpert MTB/RIF positive. Smear, culture and Xpert MTB/RIF were not done in pleural effusion.

8

Pulmonary

Lung cavity on chest CT. Positive blood T-SPOT.TB. Broncho alveolar lavage fluid smear and culture positive. Strain identification is M. Tuberculosis complex. Smear, culture and Xpert MTB/RIF were not done in sputum.

9

Pleural

Complained of fever and short of breath for 2 weeks. Less pleural effusion and no extraction. Positive blood T-SPOT.TB. Response to treatment. Smear, culture and Xpert MTB/RIF were negative in sputum.

10

Pulmonary and pleural

Lung cavity on chest CT. Pleural exudatum, MONO% 93.6% and ADA 49.8 U/L. Positive blood T-SPOT.TB. Sputum smear and culture positive. Strain identification is M. Tuberculosis complex. Sputum Xpert MTB/RIF positive. Smear, culture and Xpert MTB/RIF were not done in pleural effusion.

11

Pulmonary

Lung cavity on chest CT. Positive blood T-SPOT.TB. Sputum smear and culture positive. Strain identification is M. Tuberculosis complex. Sputum Xpert MTB/RIF positive.

12

Lumbar vertebra

Psoas abscess on lumbar vertebra MRI. Pus extracted from psoas abscess Xpert MTB/RIF positive.

13

Pleural

Pleural exudatum, MONO% 97.3% and ADA 47 U/L. Positive blood T-SPOT.TB. Smear was negative in sputum and pleural effusion, and culture and Xpert MTB/RIF were not done.

14

Pulmonary and pleural

Lung infiltrate on chest CT. Pleural exudatum, MONO% 91.7% and ADA50.4 U/L. Positive blood T-SPOT.TB. Smear, culture and Xpert MTB/RIF were negative in sputum and pleural effusion.

15

Pulmonary and pleural

Lung infiltrate on chest CT. Pleural exudatum, MONO% 100% and ADA 60.7 U/L. Positive blood and pleural T-SPOT.TB. Smear, culture and Xpert MTB/RIF were negative in sputum and pleural effusion.

16

Miliary, cerebral, hilar and mediastinal lymph nodes

Miliary shadowing, hilar and mediastinal lymph nodes enlargement on chest CT. Intracerebral tuberculomas, encephalocoele and aqueduct cerebri eclasis on head MRI. Positive blood T-SPOT.TB. Smear, culture and Xpert MTB/RIF were negative in CSF, and smear, culture and Xpert MTB/RIF were not done in sputum.

17

Miliary, pleural, cerebral and meninge

Miliary shadowing on chest CT. Pleural exudatum, MONO% 98.6% and ADA 184.3 U/L. Intracerebral tuberculomas on head MRI. Positive blood T-SPOT.TB. Abnormal CSF. CSF smear was positive. Culture and Xpert MTB/RIF were negative in CSF. Xpert MTB/RIF was negative in pleural effusion. Smear, culture and Xpert MTB/RIF were not done in sputum.

18

Pulmonary, omentum majus, abdominal lymph nodes, liver and spleen

Lung infiltrate on chest CT. Abnormal abdomen enhanced CT. Granulomas in omentum biopsy. Positive blood T-SPOT.TB. Smear, culture and Xpert MTB/RIF were not done in sputum.

19

Pulmonary, hilar and mediastina lymph nodes

Lung cavity, hilar and mediastinal lymph nodes enlargement on chest CT. Bronchoscopy bronchial stenosis. Positive blood T-SPOT.TB. Sputum smear and Xpert MTB/RIF positive. Culture was negative in sputum.

20

Pulmonary and pleural

Lung infiltrate on chest CT. Pleural exudatum, MONO% 86.1% and ADA76U/L. Positive blood T-SPOT.TB. Smear and Xpert MTB/RIF was negative in pleural effusion, but culture was not done. Smear, culture and Xpert MTB/RIF were not done in sputum.

21

Miliary

Miliary shadowing on chest CT. Positive blood T-SPOT.TB. Smear, culture and Xpert MTB/RIF were not done in sputum.

22

Miliary and cerebral

Miliary shadowing on chest CT. Intracerebral tuberculomas on head MRI. Positive blood T-SPOT.TB. Smear, culture and Xpert MTB/RIF were not done in sputum.

23

Miliary, cerebral and meninges

Miliary shadowing on chest CT. Intracerebral tuberculomas on head MRI. Abnormal CSF. Response to treatment. Smear and Xpert MTB/RIF was negative in CSF, but culture was not done. Smear, culture and Xpert MTB/RIF were not done in sputum.

24

Pulmonary

Lung infiltrate on chest CT. Sputum culture positive. Strain identification is M. Tuberculosis complex. Positive blood T-SPOT.TB. Smear and Xpert MTB/RIF were not done in sputum.

25

Pulmonary

Complained of expectoration for 1 week. Lung infiltrate on chest CT. Positive blood T-SPOT.TB. Culture was negative in sputum, but smear and Xpert MTB/RIF were not done.

26

Pulmonary

Complained of cough and expectoration for 20 weeks. Lung infiltrate on chest CT. Positive blood T-SPOT.TB. Culture was negative in sputum, but smear and Xpert MTB/RIF were not done.

27

Pulmonary

Complained of cough and expectoration for 4 weeks. Lung infiltrate on chest CT. Positive blood T-SPOT.TB. Smear, culture and Xpert MTB/RIF were negative in sputum.

28

Miliary

Complained of fever and cough for 2 weeks. Miliary infiltrate on chest CT. Positive blood T-SPOT.TB. Culture was negative in sputum, but smear and Xpert MTB/RIF were not done.