Figure 2

The levels of MMP-1, MMP-9, MMP-12, IL-17A and AhR mRNA expression in nasal tissues. The mRNA expression of MMP-1 (a) and MMP-9 (b) was significantly up-regulated in the nasal tissues of smokers with CRS and asthma (n = 13) compared to those of non-smokers with asthma and CRS (n = 16). MMP-12 expression did not differ significantly between groups (c). MMP-9 mRNA levels were correlated with IL-17A (d) and aryl hydrocarbon receptor (AhR) levels (e) in nasal tissues. IL-17A mRNA levels were correlated with AhR levels (f). The significance is indicated.