Table 2 Total bacterial and A. muciniphila copy numbers compared on a Loco-regional basis across the longitudinal axis of the colon.

From: The abundance of Akkermansia muciniphila and its relationship with sulphated colonic mucins in health and ulcerative colitis

 

n

HC

IQR

n

QUC

IQR

n

AC

IQR

Inter-cohort

Comparisons

QUC-AC

Median

Median

Median

HC-QUC

HC-AC

Total Bacterial Copy number

Caecum

20

5.07E + 7

1.17E + 8

13

1.54E + 7

2.65E + 7

19

1.47E + 5

1.07E + 6

0.065

0.000

0.002

Transverse

19

4.24E + 6

1.94E + 8

13

7.45E + 6

9.61E + 7

19

9.22E + 4

5.40E + 6

0.001

0.001

0.011

Left

19

6.20E + 7

2.12E + 8

13

1.53E + 7

4.21E + 8

19

2.11E + 5

2.68E + 6

0.935

0.001

0.002

Rectum

20

1.74E + 7

6.39E + 7

13

1.27E + 7

6.44E + 6

18

1.24E + 4

3.41E + 5

0.845

0.000

0.000

A. muciniphila Copy number

 

n

HC

IQR

n

QUC

IQR

n

AC

IQR

HC-QUC

HC-AC

QUC-AC

Median

Median

Median

Caecum

20

8.12E + 03

1.94E + 05

11

2.46E + 03

1.14E + 04

16

1.84E + 00

2.35E + 00

0.364

0.100

0.000

Transverse

18

7.74E + 03

3.87E + 04

11

1.72E + 03

4.70E + 04

13

7.15E-01

2.08E + 00

0.620

0.000

0.000

Left

16

5.44E + 03

3.66E + 04

12

2.40E + 03

3.25E + 04

18

2.74E + 00

3.02E + 00

0.516

0.000

0.000

Rectum

20

2.99E + 03

8.29E + 04

12

2.82E + 03

2.03E + 04

17

1.46E + 00

3.79E + 00

0.640

0.000

0.000

Normalised A. muciniphila Copy number

 

n

HC

IQR

n

QUC

IQR

n

AC

IQR

HC-QUC

HC-AC

QUC-AC

Median

Median

Median

Caecum

20

1.45E-04

1.21E-02

11

1.85E-04

9.51E-03

16

3.24E-06

1.40E-04

0.741

0.010

0.103

Transverse

18

5.18E-04

7.85E-03

11

2.58E-04

5.45E-04

13

1.29E-06

1.61E-04

0.393

0.028

0.077

Left

16

9.38E-05

8.45E-03

12

8.20E-05

1.67E-03

18

2.08E-05

9.14E-04

0.486

0.190

0.703

Rectum

20

8.12E-04

7.51E-03

12

1.25E-04

2.18E-03

17

2.82E-95

1.72E-03

0.259

0.072

0.425

  1. Comparison of A. muciniphila copy number on a Loco-regional basis before and after normalisation against total bacterial copy number.