Figure 2 | Scientific Reports

Figure 2

From: Neural oscillations during cognitive processes in an App knock-in mouse model of Alzheimer’s disease pathology

Figure 2

Visual discrimination (VD) touch-screen task. (a) The spider/plane stimulus image pair used in the VD25. In this example, the spider was the rewarded image (conditioned stimulus: S+) and the plane the unrewarded (unconditioned stimulus: S−) image. Image contingency was counterbalanced across animals. (b) Illustration of the VD task. A trial began with the delivery of a food pellet in the food magazine opposite to the touchscreen. Collection of the pellet initiated the trial where the two images appeared on the touchscreen. Nose-poking on the S+ stimulus activated the delivery of a food reward and the trial was registered as a correct response. Nose-poking the S− stimulus did not delivery a food reward, the light of the operant chamber went off for 5 seconds, and the response was registered as incorrect. Incorrect trials were followed by correction trials. Grey area represents local field potentials (LFPs) analysis. Epochs of 1.4 seconds immediately preceding activation of the touch-screen during correct responses were selected for electrophysiological analysis.

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