Table 1 Relative power spectral density (PSD, µV2/Hz) during the visual discrimination (VD) task.

From: Neural oscillations during cognitive processes in an App knock-in mouse model of Alzheimer’s disease pathology

Genotype

Brain Area

Freq

Condition

Mean

SD

Median

Range

N

Z

Prob > [Z]

p value rank

FDR threshold

WT

Cg

Theta

Task_Start

0.03879

0.01048

0.04082

0.03418

8

−11

0.1484

13

0.02708

Task_End

0.03639

0.00094

0.03746

0.02788

Gamma

Task_Start

0.00540

0.00110

0.00510

0.00360

8

10

0.1953

16

0.03333

Task_End

0.00560

0.00100

0.00550

0.00300

HFO

Task_Start

0.00120

0.00034

0.00120

0.00078

8

13

0.0781

9

0.01875

Task_End

0.00130

0.00036

0.00120

0.00082

App NL-G-F

 

Theta

Task_Start

0.04875

0.00666

0.04702

0.01918

7

−10

0.1094

11

0.02292

Task_End

0.04600

0.00860

0.04278

0.02300

Gamma

Task_Start

0.00450

0.00077

0.00460

0.00220

7

12

0.0469

4

0.00833

Task_End

0.00480

0.00083

0.00530

0.00220

HFO

Task_Start

0.00093

0.00020

0.00100

0.00049

7

11

0.0781

8

0.01667

Task_End

0.00099

0.00022

0.00100

0.00059

WT

dCA1

Theta

Task_Start

0.04992

0.01000

0.05291

0.03031

10

−1.5

0.9219

23

0.04792

Task_End

0.04901

0.00896

0.05110

0.02459

Gamma

Task_Start

0.00420

0.00062

0.00440

0.00200

10

4.5

0.6953

22

0.04583

Task_End

0.00440

0.00068

0.00430

0.00190

HFO

Task_Start

0.00019

0.00006

0.00020

0.00017

10

25.5

0.0059

1

0.00208

Task_End

0.00025

0.00013

0.00023

0.00049

App NL-G-F

Theta

Task_Start

0.05863

0.00790

0.06198

0.01952

6

−8.5

0.0938

10

0.02083

Task_End

0.05361

0.00862

0.05439

0.02604

Gamma

Task_Start

0.00360

0.00100

0.00330

0.00300

6

9.5

0.0625

5

0.01042

Task_End

0.00410

0.00120

0.00380

0.00380

HFO

Task_Start

0.00026

0.00011

0.00026

0.00031

6

9.5

0.0625

6

0.01250

Task_End

0.00031

0.00013

0.00032

0.00038

WT

DMS

Theta

Task_Start

0.06310

0.00684

0.06254

0.02294

8

17

0.0156

2

0.00417

Task_End

0.06634

0.00559

0.06502

0.01872

Gamma

Task_Start

0.00320

0.00076

0.00300

0.00250

8

5

0.5469

20

0.04167

Task_End

0.00330

0.00064

0.00340

0.00220

HFO

Task_Start

0.00042

0.00013

0.00037

0.00043

8

−7

0.3828

19

0.03958

Task_End

0.00041

0.00012

0.00039

0.00037

App NL-G-F

Theta

Task_Start

0.06536

0.00494

0.06540

0.01470

7

−7

0.2969

18

0.03750

Task_End

0.06330

0.01026

0.06251

0.02893

Gamma

Task_Start

0.00320

0.00069

0.00310

0.00210

7

9

0.1563

14

0.02917

Task_End

0.00360

0.00098

0.00320

0.00250

HFO

Task_Start

0.00040

0.00014

0.00039

0.00041

7

7

0.2969

17

0.03542

Task_End

0.00041

0.00014

0.00036

0.00041

WT

RSC

Theta

Task_Start

0.04116

0.00835

0.03904

0.02734

9

−13.5

0.1289

12

0.02500

Task_End

0.03915

0.00799

0.03650

0.02338

Gamma

Task_Start

0.00480

0.00088

0.00490

0.00300

9

15.5

0.0742

7

0.01458

Task_End

0.00510

0.00091

0.00510

0.00280

HFO

Task_Start

0.00119

0.00033

0.00125

0.00093

9

19.5

0.0195

3

0.00625

Task_End

0.00132

0.00031

0.00148

0.00071

App NL-G-F

Theta

Task_Start

0.04553

0.01188

0.04353

0.03560

7

−1

0.9375

24

0.05000

Task_End

0.04530

0.01254

0.04611

0.03356

Gamma

Task_Start

0.00460

0.00120

0.00460

0.00370

7

3

0.6875

21

0.04375

Task_End

0.00470

0.00120

0.00480

0.00330

HFO

Task_Start

0.00109

0.00027

0.00098

0.00073

7

9

0.1563

15

0.03125

Task_End

0.00103

0.00028

0.00110

0.00078

  1. Brain areas: Cingulate Cortex (Cg), dorsal CA1 region of the hippocampus (dCA1), dorsal medial striatum (DMS), and retrosplenial cortex (RSC).
  2. Frequencies: theta, gamma and high frequency oscillations (HFO).
  3. Conditions: Task_Start = start of the VD task, Task_End = end of the VD task.
  4. Descriptive statistics for PSD (µV2/Hz), N: sample size, Z: Wilcoxon rank-sum test.
  5. Significance level at q = 0.05, false discovery rate (FSD) corrected for multiple comparisons.
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