Table 5 Post hoc paired t-test for Mpre vs Mpos rs-FC contrast analysis in FM patients and HC.

Seed	Correlated Area	MNI Coordinates	β	T	p-FDR	Connectivity
*Fibromyalgia patients*
Pain matrix*	R PCN	01, −40, 46	−0.18	−6.2	0.02	Decreased
	R PCC	02, −18, 32	−0.17	−6.1	0.05	Decreased
	R OFC	48, 22, −14	−0.19	−7.6	0.02	Decreased
L ACC	R STG	68, −16, 04	−0.22	−7.1	<0.001	Decreased
L ACC	R SPL	18, −52, 72	−0.21	−6.2	0.04	Decreased
L AMYG	R MidFG	28, 30, 36	0.18	6.0	0.02	Increased
L AnG	R SFG	10, 16, 64	−0.22	−6.2	0.01	Decreased
	L SFG	−08, 18, 60	−0.22	−7.6	0.03	Decreased
	R PCC	02, −16, 48	−0.21	−7.1	0.05	Decreased
	R MTG	70, −16, −08	−0.25	−8.0	0.05	Decreased
	R PCN	10, −56, 28	−0.21	−7.0	0.05	Decreased
L INS	L M1	−18, −26, 56	−0.18	−8.7	0.03	Decreased
*Healthy controls*
Pain matrix*	L SLOC	−48, −50, 40	0.20	4.5	0.03	Increased
R AMYG	R SI	56, −14, 32	0.17	5.4	0.02	Increased
	L SLOC	−20, −74, 34	0.18	7.1	0.03	Increased
	R SLOC	16, −80, 44	0.20	5.0	0.04	Increased
R AnG	L LG	−14, −56, −02	0.19	5.9	0.03	Increased
R INS	L CRBL	−38, −86, −24	−0.18	−6.4	0.03	Decreased

FM, fibromyalgia patients; HC, healthy controls; Mpre, pre-music; Mpos, post-music; rs-FC, resting-state functional connectivity; β, effect size; T, T-value; p-FDR, p corrected false discovery rate; L, left; R, right. Significant seeds: Pain matrix (*12 seeds that resulted from BL analysis, merged in a post hoc mask); ACC, anterior cingulate cortex; AMYG, amygdala; AnG, angular gyrus; INS, insular cortex. Correlated areas: CRBL, cerebellum; LG, lingual gyrus; MidFG, middle frontal gyrus; MTG, middle temporal gyrus; M1, precentral gyrus (primary motor cortex); OFC, orbitofrontal cortex; PCN, precuneus; PCC, posterior cingulate cortex; SI, postcentral gyrus (primary somatosensory cortex); SFG, superior frontal gyrus; SLOC, superior lateral occipital cortex; SPL superior parietal lobe; STG superior temporal gyrus. All analyzed contrasts were corrected for multiple comparisons using the false discovery rate (FDR) at 0.05.

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