Figure 1
From: Leu8 and Pro8 oxytocin agonism differs across human, macaque, and marmoset vasopressin 1a receptors

Competition Binding of 125I-OVTA with OXT and AVP at Primate AVPR1a. Binding competition curves for AVP, Pro8-OXT, and Leu8-OXT for each of the primate AVPR1a. Increasing concentrations of competitor ligand (OXT, AVP) were added to fixed concentration of 125I-OVTA in intact CHO cells expressing one of the primate AVPR1a. All values are expressed as percentage of maximal (control) binding in the absence of OXT or AVP.