Table 3 Coupling efficiencies for ligands at primate AVPR1a.

From: Leu8 and Pro8 oxytocin agonism differs across human, macaque, and marmoset vasopressin 1a receptors

 

AVP

Leu8-OXT

Pro8-OXT

Human

−0.42

−0.64

−0.62

Macaque

0.59

−0.02

0.15

Marmoset

1.28

1.81

1.75

  1. Calculated as a Potency/Affinity Ratio [−Log(Ca2+EC50/Ki)].
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