Figure 1
From: Using high-throughput sequencing to explore the anti-inflammatory effects of α-mangostin
Strong changes in the transcriptome of IEC-6 cells stimulated with LPS or α-MG. (A) Principal components analysis (PCA) of RNA-seq data from IEC-6 cells in the LPS group (blue dots) and control group (red dots). (B) PCA of RNA-seq data from IEC-6 cells in the LPS group (red dots) and α-MG group (blue dots). (C) Venn diagram shows DEGs upregulated in the LPS group and α-MG group. (D) Venn diagram shows DEGs downregulated in the LPS group and α-MG group. (E) Volcano map showing the genes expressed in the LPS group, detected with RNA-seq. (F) Volcano map showing the genes expressed in the α-MG group, detected with RNA-seq. Colored dots indicate genes that do not differ significantly; red dots indicate genes with a log2 FC > 1 and P < 0.05; green dots indicate genes with log2 FC < −1 and P < 0.05. ‘Mangostin’ in the figure refers to α-mangostin.
