Figure 2
From: Using high-throughput sequencing to explore the anti-inflammatory effects of α-mangostin
Hierarchical clustering and heat map of the RNA-seq data for DEGs in the LPS-stimulated or α-MG -pretreated IEC-6 cells. (A) In the LPS group, 928 DEGs were significantly upregulated compared with the control group. (B) In the LPS group, 1086 DEGs were significantly downregulated compared with the control group. The whole clusters are provided in Table S1. (C) In the LPS group, 151 DEGs were significantly upregulated compared with the α-MG group. (D) In the LPS group, 324 DEGs were significantly downregulated compared with the α-MG group. The whole clusters are provided in Table S2. (E) One hundred forty-nine DEGs were upregulated in both the LPS group and α-MG group. (F) Two hundred ninety-eight DEGs were downregulated in both the LPS group and α-MG group. The whole clusters are provided in Table S3. The screening criteria by which the DEGs shown in the figure were identified were P < 0.05 and log2 FC > 1. Red indicates upregulated genes and green indicates downregulated genes. ‘Mangostin’ in the figure refers to α-mangostin.
