Figure 4
From: Using high-throughput sequencing to explore the anti-inflammatory effects of α-mangostin
The KEGG database was used to analyze the DEGs in IEC-6 cells after LPS stimulation or α-MG pretreatment. (A) Nine pathways in which the DEGs in the LPS group were significantly enriched. The whole clusters are provided in Table S6. (B) Five pathways in which the DEGs in the α-MG group were significantly enriched. The whole clusters are provided in Table S7. The pathways are shown in a bubble diagram. The Y-axis shows the relevant pathways, the bubble size and color represent the score for each pathway (Fisher’s exact was used to calculate the negative logarithmic enrichment for each pathway; enrichment was significant at P < 0.05). The larger the bubble and the closer the color is to red, the stronger is the association. ‘Mangostin’ in the figure refers to α-mangostin.
