Table 2 Logistic regression analysis to estimate the odds ratio (OR, 95% confidence interval) for TMAO in PAD patients (n = 262). Dependent variable IC/CLI.

From: Trimethylamine-N-Oxide (TMAO) Predicts Cardiovascular Mortality in Peripheral Artery Disease

 

TMAO, µmol/L a

TMAO, cutoff (>2.26 µmol/L)

 

p

≤2.26

>2.26

p

Model 1

1.84 (1.49–2.27)

<0.001

1

4.97 (2.92–8.47)

<0.001

Model 2

1.68 (1.3–2.2)

<0.001

1

4.4 (2.1–9.1)

<0.001

  1. aLog-transformed variable. Unadjusted Model 1. Model 2: sex, age, smoking, diabetes mellitus, hypertension, dyslipidemia, HDL-C, eGFR (<60 mL/min/1.73 m2), and hs-CRP (log-transformed).