Figure 4
From: Biofilm-stimulated epithelium modulates the inflammatory responses in co-cultured immune cells

Histology of human gingival epithelium model. Haematoxylin and eosin (H&E) stained histological section of human gingival epithelium (HGE) showing the characteristic 6–8 epithelial layers of gingival tissue. The H&E stained epithelium could be further divided into characteristic cellular layers as depicted by (A–D) (basal cell layer, (A); prickle cell layer, (B); granular layer, (C); keratinised layer, (D)). Keratinocytes within the granular layer are identified by the presence of keratohyalin granules, shown as by the white arrows. Terminally differentiated keratinocytes (corneocytes), are identified by black arrows. Histological image representative of an unstimulated HGE tissue.