Figure 5
From: Metabolomic studies in tissues of mice treated with amifostine and exposed to gamma-radiation
(A) Amifostine treatment results in modest changes in metabolite profiles of jejunum. (panel A) Circos plot showing most correlated metabolite patterns (panel B) Raindrop illustration of metabolite patterns that correlate with radioprotection in jejunum with 50 and 200 mg/kg of amifostine at 4 and 9 d post-irradiation. (B) Amifostine treatment results in modest changes in metabolite profiles of lung. (panel C) Circos plot showing most correlated metabolite patterns (panel D) Raindrop illustration of metabolite patterns (union set) that correlate with radioprotection in lung with 50 and 200 mg/kg of amifostine at 4 d and 9 d post-irradiation.
