Table 1 Radiation induced pathway dysregulation in bone marrow at 4 and 9 days post-irradiation.
From: Metabolomic studies in tissues of mice treated with amifostine and exposed to gamma-radiation
Pathway | Day 4 | Day 9 | ||
|---|---|---|---|---|
overlap size | p-value | overlap size | p-value | |
Carnitine shuttle | 22(22)a | 2.27E-03 | — | — |
Tyrosine metabolism | 6(6) | 1.24E-02 | 10(10) | 1.93E-02 |
Phosphatidylinositol phosphate metabolism | 5(5) | 2.21E-02 | 5(5) | 3.68E-02 |
Histidine metabolism | 4(4) | 3.53E-02 | — | — |
Bile acid biosynthesis | 4(4) | 3.53E-02 | — | — |
Xenobiotics metabolism | — | — | 7(7) | 4.73E-02 |
