Table 2 Metabolic changes in bone marrow, jejunum, and lung in response to amifostine treatment at 200 mg/kg.
From: Metabolomic studies in tissues of mice treated with amifostine and exposed to gamma-radiation
Name | Organ/Tissue | p-value | FDR a | Fold Change | Log2(FC) |
|---|---|---|---|---|---|
PG(18:0/20:4) | Bone marrow | 2.61E-05 | 2.69E-02 | 1.4681 | ↑ 0.5540 |
PC(O-16:0/20:4) | Bone marrow | 3.77E-02 | NS | 1.1399 | ↑ 0.1889 |
PA(18:0/20:4) | Bone marrow | 3.33E-02 | NS | 1.1413 | ↑ 0.1907 |
PE(P-16:0/22:6) | Bone marrow | 1.20E-03 | NS | 1.2031 | ↑ 0.2668 |
PG(18:0/22:6) | Bone marrow | 1.53E-02 | NS | 1.2523 | ↑ 0.3246 |
PE(18:0/22:6) | Bone marrow | 2.07E-02 | NS | 2.0152 | ↑ 1.0110 |
PC(p-18:0/18:1) | Bone marrow | 3.72E-02 | NS | 1.2359 | ↑ 0.3056 |
PC(18:0/22:6) | Bone marrow | 3.40E-02 | NS | 1.2078 | ↑ 0.2724 |
PG(16:0/18:1) | Bone marrow | 1.60E-02 | NS | 1.3228 | ↑ 0.4036 |
N-Stearoyl taurine | Bone marrow | 2.95E-02 | NS | 1.1863 | ↑ 0.2465 |
PC(18:0/20:4) | Bone marrow | 2.64E-02 | NS | 1.2759 | ↑ 0.3515 |
PE(16:0/20:4) | Bone marrow | 2.06E-02 | NS | 1.1394 | ↑ 0.1882 |
GPE(P-18:0/20:4) | Bone marrow | 1.24E-02 | NS | 1.1534 | ↑ 0.2059 |
Oleoyl-L-carnitine | Bone marrow | 3.63E-02 | NS | 0.6242 | ↓ −0.6799 |
PI(20:4/0:0) | Jejunum | 4.33E-02 | NS | 0.6477 | ↓ −0.6266 |
L-Cysteine-glutathione disulfide | Jejunum | 2.42E-02 | NS | 0.4403 | ↓ −1.1835 |
Docosahexaenoylglycine | Jejunum | 1.50E-02 | NS | 0.7432 | ↓ −0.4282 |
Tauroursodeoxycholic acid | Jejunum | 1.58E-03 | NS | 1.5609 | ↑ 0.6424 |
Hydroxyphenyl-2-hydroxyethyl oleamide | Lung | 1.14E-13 | 3.91E-10 | 31.1710 | ↑ 4.9621 |
Lyso-SM | Lung | 1.74E-02 | NS | 0.7263 | ↓ −0.4614 |
