Table 3 The interactive effect between maternal pre-pregnancy BMI status and BP status during pregnancy on high BMI status in infants at 12 months old†.

From: The interactive effect of pre-pregnancy overweight and obesity and hypertensive disorders of pregnancy on the weight status in infancy

Pre-pregnancy BMI status‡

BP status during pregnancy‡

Model1†

P-value

Model2†

P-value

Model3†

P-value

OR (95% CI)

OR (95% CI)

OR (95% CI)

Non-OWO‡

NBP‡

Reference

 

Reference

 

Reference

 

Non-OWO‡

HDP‡

1.41 (0.96, 2.09)

0.083

1.36 (0.92, 2.03)

0.126

1.34 (0.90, 2.00)

0.146

OWO‡

NBP‡

1.22 (0.93, 1.60)

0.147

1.18 (0.90, 1.56)

0.235

1.18 (0.89, 1.56)

0.240

OWO‡

HDP‡

3.57 (1.85, 6.88)*

<0.001

3.25 (1.67, 6.31)**

0.001

3.10 (1.59, 6.04)**

0.001

Multiplicative interaction

OWO*HDP‡

2.07 (0.93, 4.61)

0.075

2.01 (0.89, 4.53)

0.091

1.95 (0.87, 4.40)

0.107

Additive interaction

OWO*HDP (RERI/AP)‡

1.94 (−0.47, 4.34)/0.54 (0.20, 0.89)

 

1.70 (−0.53, 3.92)/0.52 (0.16, 0.89)

 

1.58 (−0.56, 3.71)/0.51 (0.13, 0.89)

 
  1. †Logistic regression analysis. Model1: Unadjusted model; Model2: Adjusted for cohort, infant sex, gestational age, infant birth weight and length, delivery mode, maternal age and maternal gestational weight gain; Model 3: Adjusted for potential variables in Model2 plus maternal education level, household income, secondhand smoke exposure, and feeding patterns at 1 month. ‡AP, attributable proportion; RERI, relative excess risk due to interaction; BMI: body mass index; BP: blood pressure; Non-OWO: non-overweight or obesity; OWO: overweight or obesity; NBP: normal blood pressure; HDP: hypertensive disorders of pregnancy.
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