Table 1 Patient characteristics.

From: Correlation of axial length and myopic macular degeneration to levels of molecular factors in the aqueous

n

Control group

High myopia without myopic macular degeneration

High myopia with myopic macular degeneration

P-trend**

P-value††

14

12

12

Age, years

63.9 ± 6.2

59.1 ± 8.6

63.8 ± 10.1

0.86

0.28

Female Gender (%)

5 (36%)

6 (50%)

11 (91.2%)

0.01

0.01*

Axial Length, mm

24.3 ± 1.1

28.1 ± 1.5

29.5 ± 1.2

<0.001

<0.001†

Subfoveal Choroidal thickness, um

215 ± 21

80.3 ± 67.0

51.5 ± 33.3

0.001

<0.001‡

  1. *Pairwise comparison with Bonferroni correction: controls vs high myopes without myopic macular degeneration (MMD), p < 0.001; controls vs high myopes with MMD, p < 0.001; high myopes without MMD vs high myopes with MMD, p = 0.002.
  2. †Pairwise comparison with Bonferroni correction: controls vs high myopes without MMD, p < 0.001; controls vs high myopes with MMD, p < 0.001; high myopes without MMD vs high myopes with MMD, p = 0.057.
  3. ‡Pairwise comparison with Bonferroni correction: controls vs high myopes without MMD, p = 0.001; controls vs high myopes with MMD, p < 0.001; high myopes without MMD vs high myopes with MMD, p = 0.90.
  4. **P-trend was analyzed across the ordinal categories of controls, high myopia without MMD and high myopia without MMD. A two-tailed P-value of <0.05 was considered statistically significant.
  5. ††P-value was obtained using one way analysis of covariance (ANOVA) across the 3 groups. A two-tailed P-value of <0.05 was considered statistically significant.
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