Figure 3 | Scientific Reports

Figure 3

From: Optimal Inhibition of Choroidal Neovascularization by scAAV2 with VMD2 Promoter-driven Active Rap1a in the RPE

Figure 3

scAAV2-VMD2 vector shows more specific GFP transduction and greater Rap1 expression in the RPE. (A) IHC of GFP in retinal cryosections (Blue: TO-PRO-3; Green: GFP) (B–E) western blots of Rap1a and β-actin in RPE/choroids (B–D), (representative gel images and C and E, quantification of densitometry) of wild type mice injected with either (B,C) scAAV2-RPE65 or (D,E) scAAV2-VMD2 or PBS (*p < 0.05 vs. scAAV2-VMD2-GFP; †p < 0.05 vs. PBS n = 5–6.

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