Figure 4

Expression of active Rap1a in RPE by scAAV2-VMD2-CARap1a reduces choroidal neovascularization (CNV) in wild type mice in a laser induced CNV model. (A) Representative images of RPE/choroid flat mounts and (B) quantification of CNV lesion (*p < 0.05 vs. scAAV2-VMD2, n = 40 spots from 12 mice).