Figure 5 | Scientific Reports

Figure 5

From: Optimal Inhibition of Choroidal Neovascularization by scAAV2 with VMD2 Promoter-driven Active Rap1a in the RPE

Figure 5

Expression of active Rap1a in RPE by scAAV2-VMD2-CARap1a reduces inflammation and VEGF in RPE/choroids. Western blots of (A,B) phosphorylated NF-κB (p-NF-κB) and (C,D) VEGF in RPE/choroids of scAAV2-VMD2 injected wild type mice 7 days after laser treatment (A–C), representative gel images and (B–D), quantification of densitometry; *p < 0.05, **p < 0.01 vs. scAAV2-VMD2-GFP; n = 6–8.

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