Figure 7
Expression of active Rap1a in RPE by adenovirus transduction reduces VEGF and NF-κB activation. Western blots of (A,B) Rap1, (C,D) VEGF protein and (E,F) phosphorylated NF-κB (p-NF-κB) and total NF-κB in human RPE transduced with adenovirus expressing GFP (Ad-GFP) or GFP and constitutively active Rap1a (Ad-63E) (A,C,E), representative gel images and (B,D,F), quantification of densitometry *p < 0.05, **p < 0.01 vs. Ad-GFP; n = 3.
