Figure 1 | Scientific Reports

Figure 1

From: Cigarette smoke affects the onco-suppressor DAB2IP expression in bronchial epithelial cells of COPD patients

Figure 1

Immunoreactivity for EZH2, H3K27me3 and DAB2IP in bronchial epithelial cells (cell/mm) from Control (n = 8), Smokers (n = 8), COPD ex-smoker (n = 8) and COPD smoker (n = 10) subjects. Cells were stained with the following antibodies: (A) anti-EZH2, (B) anti-H3K27me3; (C) anti-DAB2IP. Negative Control (NC) was performed using rabbit immunoglobulins. The scale bar is 50 µm. Counts for the number of positive epithelial cells/mm, basement membrane are shown. Bars represent mean ± SD of positive bronchial epithelial cells/mm basement membranes. Representative Immunostaining of EZH2, H3K27me3 and DAB2IP in Control (n = 8), Smoker (n = 8), COPD ex-smokers (n = 8) and COPD Smokers (n = 10) subjects at 40× magnification is shown. Statistical analysis was performed by Student’s t-test. Significance was accepted at p < 0.05.

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