Figure 3 | Scientific Reports

Figure 3

From: GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome

Figure 3

After liraglutide treatment, there was an increased number of neurons in Wfs1 KO animals’ dorsal nucleus. Stereological quantification of the total number of neurons in the inferior olive after 6 months of liraglutide treatment. Total number of neurons in (a) medial nucleus, (b) dorsal nucleus, (c) principal nucleus, and (d) in all inferior olive (IO) nuclei together. The data were compared using factorial ANOVA followed by Fisher’s LSD tests; *p < 0.05. The data are presented as the mean ± SEM, n = 4–8 per group.

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