Figure 5 | Scientific Reports

Figure 5

From: The Cholesteryl Ester Transfer Protein Inhibitor, des-Fluoro-Anacetrapib, Prevents Vein Bypass-induced Neointimal Hyperplasia in New Zealand White Rabbits

Figure 5

Cellular characterization of grafted veins in NZW rabbits treated with des-fluoro-anacetrapib. Right external jugular vein autologous end-to-side transplantation bypass grafting of the right common carotid artery was carried out in NZW rabbits maintained on regular chow (control, n = 8) or chow supplemented with 0.14% (wt/wt) des-fluoro-anacetrapib (dfAna, n = 9) as described in the legend to Fig. 1. Representative photomicrographs of grafted vein cross-sections (bar = 50 µm) from control and dfANa-treated animals immunostained for α-SMC actin (Panel A), CD18 (Panel B, red arrows) and RAM11 (Panel C) are shown.

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