Table 1 Characteristic parameters of the effects of FE on the properties of lipid bilayers: Gmodifier/Gcontrol – ratio of the membrane conductance of FE channels in the absence and presence of membrane modifiers at V = ±50 mV; Δφb – change in the membrane boundary potential related to its dipole component; ΔTm – change in the main transition temperature of DPPC after the addition of modifier to the suspension of liposomes; ΔT1/2 – change in the half-width of the peak.
From: Fengycin induces ion channels in lipid bilayers mimicking target fungal cell membranes
modifiers | C, μM | G modifier /G control a | Δφb, mVb | −ΔTm, °C | ΔT1/2, °C |
|---|---|---|---|---|---|
Phloretin | 20 | 3.8 ± 1.6 | −70 ± 2 | 1.2 | 1.9 |
Myricetin | 20 | 1.0 ± 0.1 | 5 ± 2 | 0.1 | 0.2 |
T 3 | 50 | 4.7 ± 1.5 | −60 ± 8 | 0.8# | 0.2 |
RH 421 | 5 | 1.3 ± 0.2 | 90 ± 15 | 0.1 | 0.2 |
TTC | 1000 | 5.4 ± 2.1 | 80 ± 12 | 3.5$ | 0.7 |
TX-100 | 10 | 2.1 ± 0.5 | 1 ± 1 | 2.4 | 1.6 |
Caffeine | 1000 | 1.0 ± 0.1 | 3 ± 1 | 0 | 0 |
