Table 1 List of the Ψ-modified RNA duplexes and their unmodified counterparts studied in this work.
From: Computational and NMR studies of RNA duplexes with an internal pseudouridine-adenosine base pair
Duplex name | Sequence | Method | Duplex name | Sequence | Method | |
|---|---|---|---|---|---|---|
NMR | MD | MD | ||||
duplex-GΨC | 5′-UCAGΨCAGU-3′ 3′-AGUCAGUCA-5′ | ✓ | ✓ | duplex-GUC | 5′-UCAGUCAGU-3′ 3′-AGUCAGUCA-5′ | ✓ |
duplex-CΨG | 5′-UCACΨGAGU-3′ 3′-AGUGACUCA-5′ | ✓ | ✓ | duplex-CUG | 5′-UCACUGAGU-3′ 3′-AGUGACUCA-5′ | ✓ |
duplex-AΨU | 5′-UCAAΨUAGU-3′ 3′-AGUUAAUCA-5′ | ✓ | duplex-AUU | 5′-UCAAUUAGU-3′ 3′-AGUUAAUCA-5′ | ✓ | |
duplex-UΨA | 5′-UCAUΨAAGU-3′ 3′-AGUAAUUCA-5′ | ✓ | duplex-UUA | 5′-UCAUUAAGU-3′ 3′-AGUAAUUCA-5′ | ✓ | |
