Table 1 Daemographics. Basic Measurements. Comorbidities.

From: Range Variability in CMR Feature Tracking Multilayer Strain across Different Stages of Heart Failure

 

Controls

HFpEF

HFmrEF

HFrEF

P Value

Patients in group, n

17

18

21

20

 

Age, y

63.9 ± 6.9

71.5 ± 7.1

68.3 ± 9.4

64.7 ± 9.2

0.12

Male subjects

9

9

13

12

0.75

Heart rate (bpm)

60.2 ± 9.4

63.5 ± 9.1

65.8 ± 8.5

66.1 ± 10.0

0.23

LVEDV (ml)

126 ± 31

120 ± 31

173 ± 32

244 ± 73

<0.001§

LVEDVi (ml/m2)

64 ± 11

62 ± 14

90 ± 15

116 ± 31

<0.001§

LVESV (ml)

45 ± 16

48 ± 17

96 ± 20

164 ± 51

<0.001§

LVESVi (ml/m2)

25 ± 2

27 ± 9

53 ± 11

91 ± 28

<0.001§

LV Stroke Volume (ml)

81 ± 16

72 ± 18

77 ± 14

80 ± 26

0.87

LA Surface (cm2)

20.4 ± 4.1

21.1 ± 6.0

23.1 ± 6.8

27.7 ± 6.1

0.003§

RA Surface (cm2)

22.4 ± 5.2

21.6 ± 6.0

20.1 ± 4.5

21.6 ± 4.8

0.65

LVEF (%)

64.4 ± 5.2

60.0 ± 7.2

44.2 ± 3.0

32.3 ± 6.0

<0.001§

LV-EDD(mm)

49.1 ± 4.4

50.7 ± 4.3

57.4 ± 5.9

65.4 ± 7.5

<0.001§

Septum(mm)

9.2 ± 1.7

11.2 ± 2.2

11.7 ± 1.7

11.8 ± 3.0

<0.001§

Lateral Wall(mm)

7.2 ± 1.0

7.4 ± 1.5

7.1 ± 1.7

8.1 ± 2.2

0.35

LVM (g)

93 ± 24

83 ± 23

112 ± 38

143 ± 40

<0.001§

LVMi (g/m2)

47.4 ± 9.2

43.4 ± 8.9

104.0 ± 48.3

131.2 ± 50.5

<0.001§

E/e′ ratio

10.9 ± 3.9

11.1 ± 4.3

11.1 ± 1.6

14.8 ± 6.2

0.09

NT-proBNP (ng/l)

94 ± 62

451 ± 512

885 ± 1146

2198 ± 3479

0.007§

Laboratory Values

Hemoglobin (g/dl)

13.9 ± 1.1

13.0 ± 1.3

13.7 ± 1.1

15.0 ± 1.1

 

Hematocrit

0.40 ± 0.03

0.38 ± 0.03

0.40 ± 0.03

0.44 ± 0.04

 

Creatinin (mg/dl)

0.87 ± 0.20

0.92 ± 0.18

1.06 ± 0.33

1.10 ± 0.39

 

GFR (ml/min)

81 ± 10

71 ± 15

71 ± 18

71 ± 21

 

Troponin T (ng/l)

7 ± 3

20 ± 17

19 ± 20

19 ± 12

 

CRP (mg/dl)

1.3 ± 1.4

2.9 ± 2.5

2.9 ± 4.1

1.0 ± 0.7

 

WBC (n/nl)

6.1 ± 1.6

7.1 ± 2.3

8.4 ± 2.3

8.5 ± 2.4

 

Comorbidities, risk factors

CAD

0

12

14

11

<0.001§

Peripheric Artery Disease

0

5

3

2

0.11

Hypertension

6

12

15

12

0.12

Diabetes

2

4

5

3

0.72

Hypercholesterolemia

4

12

14

11

0.031§

COPD

0

1

3

1

0.34

Smokers

6

7

8

6

0.94

  1. LVEDV – left ventricle end diastolic volume, LVEDVi – left ventricle end diastolic volume index, LVESV – left ventricle end systolic volume, LVEF – LV ejection fraction, LV-EDD – left ventricle end diastole diameter, LA – left atrium, RA – right atrium, LVM – left ventricle mass, LVMi – left ventricle mass index, CAD – coronary artery disease, COPD – Chronic obstructive pulmonary disease. Values are given as mean ± SD unless stated otherwise. Comparison between groups are assessed through an ANOVA 1-way. P values were adjusted with the Bonferroni method, a level above 0.05 is considered significant. §Significant.
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